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
While ivermectin is FDA-approved for treating certain parasitic infections, it hasn’t been authorised for COVID-19 treatment or prevention.
You should be aware of potential side effects, which can range from mild symptoms like itching and dizziness to severe reactions affecting the nervous system, skin, and eyes.
Please consult your healthcare provider about the safe use of ivermectin, as it may interact with other medications you’re taking.
Special precautions apply if you’re pregnant, breastfeeding, elderly, or have liver or kidney disease.
To guarantee your safety and well-being, it’s vital to understand the risks and benefits before considering this medication.
Key Takeaways
- Ivermectin is FDA-approved for treating certain parasitic infections but is not authorised for COVID-19 treatment or prevention.
- Misuse of veterinary formulations can cause serious toxicity, including seizures, coma, and death.
- Common side effects include itching, dizziness, and nausea; severe CNS, skin, and eye reactions require immediate medical attention.
- Ivermectin interacts with various medications, and alcohol should be avoided while taking it.
- Consultation with healthcare providers is crucial for safe use, considering individual health conditions and regular monitoring for side effects and interactions.
Safety Concerns
Ivermectin, though approved for certain parasitic conditions, hasn’t been authorised or approved by the FDA for the treatment of COVID-19.
Misuse of ivermectin, particularly using products intended for animals, poses severe health risks.
Adverse event reports have increased due to inappropriate topical and veterinary formulations.
Serious toxicity symptoms from ivermectin misuse can include seizures, coma, low blood pressure, and even death.
It’s vital to be aware that ivermectin may interact with other medications like warfarin, increasing the risk of toxicity.
Regulatory warnings have been issued regarding the dangers of ivermectin misuse.
The CDC released a health advisory on 26th August 2021, cautioning about the rapid increase in ivermectin prescriptions and associated severe illnesses.
The FDA has repeatedly warned against using ivermectin for COVID-19 and highlighted the risks of using veterinary products.
Poison control centres have reported an increase in calls related to ivermectin exposure.
All significant or unusual adverse drug events should be reported to the FDA MedWatch programme.
Public education efforts by health organisations aim to raise awareness about the risks of misusing ivermectin.
It’s essential to use ivermectin only under the guidance of a healthcare provider and for approved indications.
Special precautions should be taken for pregnant or breastfeeding individuals.
Patients should inform their healthcare providers of all their medications to avoid potential interactions.
Regular monitoring is necessary for patients on ivermectin, particularly those with conditions affecting the immune system.
In cases of suspected overdose or toxicity, immediate medical attention is required.
Common Side Effects
What are some of the most frequently reported side effects of taking ivermectin?
According to the available data, common side effects include itching sensations on the skin, dizziness issues, fluid retention, rapid heartbeat, and diarrhoea.
While these side effects are generally considered mild, they can still cause discomfort and concern for those taking the medication.
Common side effects also include nausea, a side effect reported by many ivermectin users.
Other common but typically mild side effects of ivermectin include headaches, muscle aches, nausea, mild skin rashes, and loss of appetite.
It’s important to monitor these symptoms and consult a healthcare professional if they persist or become bothersome.
In some cases, more severe side effects may require prompt medical attention.
These include eye or redness, puffy eyes, joint pain and swelling, abnormal eye sensations, and fever.
If you experience these symptoms while taking ivermectin, seeking medical advice is vital.
Additional side effects that have been reported include stomach pain or bloating, constipation, weakness, uncontrollable shaking of a part of the body, and chest discomfort.
While these side effects may not always be severe, they should still be monitored and reported to a healthcare provider if they cause significant discomfort or persist over time.
It’s essential to be aware of the potential side effects when taking ivermectin and to follow the prescribed dosage and duration of treatment.
If you have any concerns or questions about the side effects or your response to the medication, don’t hesitate to consult your healthcare provider for guidance and support.
Serious Side Effects
While ivermectin is generally well-tolerated, it’s vital to be aware of the potential for serious side effects that require immediate medical attention.
Although rare, these serious reactions can affect various body systems, including the brain and central nervous system (CNS), skin, and eyes, and even cause severe allergic reactions.
Liver damage is another potential serious side effect.
If you experience any of the following symptoms, seek medical help right away:
- Sluggishness, sleepiness, confusion, disorientation, reduced responses, or loss of consciousness
- Breathing problems, wheezing, racing heart, fever, swollen lymph nodes, or swelling of the face, lips, mouth, tongue, or throat
- Severe skin rash, itching, rash with pus, blistering, or peeling skin
- Eye pain, redness, puffiness, vision problems, or abnormal eye sensations
- Swelling of the eyes, face, arms, hands, feet, ankles, or lower legs
It’s important to be vigilant about these potential side effects and to inform your healthcare provider if you have any pre-existing conditions or allergies that may increase your risk.
In the event of an overdose, symptoms may include sleepiness, skin rash, swelling, headache, dizziness, nausea, vomiting, diarrhoea, or confusion.
If you suspect an overdose, contact poison control or seek emergency medical attention immediately.
While serious side effects are rare, weighing the potential risks against the benefits of taking ivermectin is significant.
To ensure the safe and effective use of this medication, always follow the prescribed dosage and discuss any concerns with your healthcare provider.
Use and Indications
Approved by the FDA for treating river blindness (onchocerciasis) and intestinal strongyloidiasis, ivermectin is also used off-label to treat other parasitic infections.
For onchocerciasis, dosage guidelines are based on body weight categories, with 0.15 mg/kg given orally once every 12 months.
Treatment may be repeated every 3 to 12 months, and patients with heavy ocular infection may require retreatment every 6 months.
The recommended dose is 0.2 mg/kg orally once when treating intestinal strongyloidiasis.
In immunocompromised patients, treatment may be repeated every 2 weeks, although a cure may not be achievable.
Ivermectin has shown effectiveness against various parasitic worms and exhibits antiviral activity against certain RNA and DNA viruses.
Topical use of ivermectin is approved for treating head lice and rosacea.
Off-label uses include treating scabies and pediculosis capitis, with specific dosing varying based on the condition.
Recognising that the FDA hasn’t authorised ivermectin for treating or preventing COVID-19 is crucial.
Ivermectin is available in tablet form, with each tablet containing 3 mg of the active ingredient.
If you miss a dose, take it as soon as possible unless it’s almost time for the next one.
Always follow the prescribed dosage guidelines and consult your healthcare provider if you have questions or concerns about using ivermectin.
Interactions and Precautions
When taking ivermectin, it’s important to be aware of potential interactions with other medications and take precautions regarding side effects.
Ivermectin can interact with various drugs, including blood thinners, antibiotics, antivirals, and cardiovascular medications.
These interactions may increase the drugs’ toxicity or decrease their elimination from the body, leading to higher serum concentrations.
Ivermectin enhances the metabolism of various drugs, including anti-epileptics and glucocorticoids, while its serum concentration can be affected by drugs like azithromycin and ritonavir.
It’s vital to inform your healthcare provider about all the medications you’re taking to avoid potentially dangerous drug interactions.
Special precautions should be taken when using ivermectin, especially in vulnerable populations:
- Pregnant and breastfeeding women should consult their healthcare providers before taking ivermectin due to potential risks to the foetus or baby.
- Elderly patients may have increased sensitivity to side effects and a higher risk of drug interactions.
- Patients with liver or kidney disease may require dose adjustments.
- Immunocompromised patients should use caution due to potential increased susceptibility to infections.
- Patients taking multiple medications should have their drug interactions carefully evaluated.
Be vigilant for severe side effects such as allergic reactions, central nervous system problems, eye and vision issues, fever, swelling, dizziness, and fainting.
These symptoms require immediate medical attention.
Alcohol consumption should be avoided while taking ivermectin, as it can enhance side effects like dizziness and sleepiness, reduce alertness, and impair judgment.
Frequently Asked Questions
How Long Has Ivermectin Been Used in Humans and Animals?
Ivermectin has a long historical context of use in both humans and animals.
It has been a veterinary staple since 1981, treating parasitic infections in livestock and pets.
In humans, it has been approved for treating tropical diseases such as onchocerciasis and strongyloidiasis since 1987.
While its primary applications are antiparasitic, researchers cautiously explore its potential for other uses due to its unique properties.
Is it available over-the-counter or prescription only?
Ivermectin accessibility isn’t straightforward.
You can obtain the topical lotion over the counter, but Ivermectin regulations require a prescription for oral tablets and topical cream.
The drug is available in various forms, each treating different conditions.
To stay safe, follow your doctor’s instructions when taking any form of ivermectin.
Costs vary based on insurance coverage, treatment plans, and where your prescription is filled.
What Is the Recommended Dosage of Ivermectin for Various Conditions?
Ivermectin’s efficacy varies by condition, so dosage recommendations differ.
You’ll typically take 0.2 mg/kg orally for parasitic infections like ascariasis and strongyloidiasis.
For onchocerciasis, you might take 0.15 mg/kg every 6-12 months.
Scabies treatment is 0.2 mg/kg, repeated in 2 weeks.
Weight-based dosing ranges from 3-15 mg for adults.
Paediatric dosing mirrors adult guidelines for those over 15 kg.
Always consult a healthcare professional for personalised dosing.
How Quickly Does Ivermectin Start Working After Administration?
You may wonder how quickly ivermectin takes effect after taking it.
Its onset time is rapid – peak concentrations are reached within 4-8 hours.
You’ll start seeing effectiveness within a few days as it suppresses parasite nerve impulses.
A single dose provides antiparasitic activity lasting several months.
Are There Any Long-Term Effects Associated With Ivermectin?
Research on long-term effects is limited, as most studies focus on short-term use.
While generally well-tolerated, some long-term studies suggest potential risks such as liver damage, neurological problems, and serious eye issues.
Rare but severe side effects may include allergic reactions and cardiovascular complications.
More research is needed to understand ivermectin’s long-term safety profile fully.
Following prescribed dosing and discussing any concerns with your doctor is essential.
Conclusion
While ivermectin has shown promise in treating various conditions, it should be cautiously approached like a tightrope walker.
Please consult your doctor to verify it suits you and avoid potential interactions with other medications.
Though generally safe, ivermectin can cause side effects ranging from mild to severe.
As with any drug, it is essential to weigh the potential benefits against the risks before deciding whether ivermectin is the key to improving health.
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