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Blu Brain (1% Methylene Blue) and Sleep: Solving Nighttime Disruptions and Optimising Rest
Reading Time: 4 minutes. Hey Blu Brain users! Just wanted to share some insights and hear about your experiences with Blu Brain, especially in relation to sleep improvements. Since incorporating Blu Brain (1% methylene blue) into my routine, I’ve noticed significant enhancements not only in sleep quality but also in overall brain health. Here’s a…
Riding The Waves: Mental Well-Being During The Menstrual Cycle
Reading Time: 15 minutes. Navigating the turbulent sea of hormonal fluctuations during the menstrual cycle can be a daunting task. Like an unpredictable storm, it can rise and fall at varying intervals, causing a range of emotions and physical discomfort. The interplay between these hormones not only affects physiological aspects but also significantly impacts mental…
Unlock Your Brain’s Potential: Top 10 Biohacking Strategies For Cognitive Enhancement
Reading Time: 7 minutes. Neuroplasticity, the brain’s remarkable ability to reorganise and adapt itself, is a theory that has revolutionised how we perceive human potential. This potent concept forms the basis of biohacking – strategic lifestyle modifications to enhance cognitive performance. For those seeking to unlock their cerebral prowess, this article unveils the top 10…
Can Methylene Blue Be a Game-Changer for Treating Depression?
Reading Time: 7 minutes. Methylene blue, a medication with a long history of treating various conditions, is gaining attention for its potential to revolutionise depression treatment. You may find it promising to know that methylene blue enhances the production of serotonin and norepinephrine, essential neurotransmitters for mood regulation, through neurotransmitter modulation, MAO A inhibition, and…
Mastering Methylene Blue Dosage: A Comprehensive Guide
Reading Time: 5 minutes. Mastering methylene blue dosage requires accuracy in understanding its concentration, typically a 1% solution with a concentration of 10 mg/mL. Individual dosages should be tailored based on body weight, ranging from 0.5 mg/kg to 4 mg/kg per kilogram of body weight. For a 70 kg individual, the daily dose ranges from…
Risks and Safety Concerns of Methylene Blue in Medicine
Reading Time: 10 minutes. Methylene blue presents significant medical risks requiring careful consideration in clinical settings. Key concerns include severe drug interactions, particularly with serotonergic medications, potentially leading to serotonin syndrome. Common side effects encompass skin/urine discolouration (13% of patients), gastrointestinal symptoms, and cardiovascular complications. The compound poses serious risks during pregnancy (31.8% fetal mortality…
Exploring the Relationship Between Methylene Blue and Nitric Oxide
Reading Time: 4 minutes. Methylene blue notably affects nitric oxide synthesis by inhibiting nitric oxide synthase (iNOS) and soluble guanylyl cyclase. This action disrupts key intracellular processes, modulating nitric oxide production and regulating vascular tone. Methylene blue‘s inhibition of iNOS, independent of calcium, reduces nitric oxide levels, thereby attenuating vasodilation. These mechanisms are crucial in…
Methylene Blue: A Novel Approach to Managing Fibromyalgia and Chronic Pain?
Reading Time: 4 minutes. Hey everyone! I recently came across some intriguing research on Methylene Blue and its potential effects on fibromyalgia and chronic pain management. For those unfamiliar, Methylene Blue is primarily known as a dye, but it has also been used in medicine for over a century. What caught my attention was how…
Risks of Overusing Methylene Blue: What to Know
Reading Time: 16 minutes. You’ll face severe health risks when exceeding recommended methylene blue dosages, particularly doses above 2 mg/kg or cumulative amounts over 7 mg/kg. Watch for dangerous symptoms such as blue-stained skin, breathing difficulties, confusion, and gastrointestinal distress. The drug’s longer half-life means toxicity can persist for 24 hours post-administration, requiring close monitoring.…
