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Understanding Long-Term Risks of Methylene Blue Usage
Reading Time: 14 minutes. Long-term exposure to methylene blue poses significant health risks, necessitating careful monitoring. Chronic use can lead to cumulative oxidative stress, affecting the cardiovascular, renal, and neurological systems. At doses exceeding 5 mg/kg, patients risk developing methemoglobinemia, serotonin toxicity, and severe organ complications. The compound exhibits a biphasic response: while low doses…
Methylene Blue: A Ray of Hope for Alzheimer’s and Dementia Patients?
Reading Time: 4 minutes. Hey everyone in the Brain Health Blog Forum! I recently came across some intriguing research on Methylene Blue and its potential benefits for patients with Alzheimer’s and dementia. I thought it would be great to share what I’ve learned and see if anyone else here has any insights or experiences with…
Methylene Blue Dosage Chart by Body Weight: Safe Guidelines With Blu Brain
Reading Time: 6 minutes. You’ll need to calculate the methylene blue dosage based on your body weight to stay within safe therapeutic ranges. Clinical guidelines recommend keeping doses under 2 mg per kilogram, as toxicity begins around 7 mg/kg. For cognitive benefits, research suggests 4-30 mg daily is both safe and effective. The compound follows…
Methylene Blue and Long Covid: Current Theories and Ongoing Research
Reading Time: 11 minutes. Methylene blue is being explored for Long COVID due to antiviral actions (spike–ACE2 blockade, Zn2+ ionophore effects, RdRp inhibition, lysosomal pH elevation) and immunomodulation (NLRP3, NF-κB, PD-1–SHP2). In vitro data show low micromolar inhibition; small acute COVID-19 trials suggest improved SpO2 and inflammatory markers without a clear mortality benefit. Its mitochondrial…
The Power of Active Listening and Empathy in Relationships
Reading Time: 5 minutes. As you practise active listening and empathy, you’ll transform your relationships into meaningful connections that foster trust and understanding. By focusing on the speaker’s emotions and needs, you create a safe space for open dialogue, which deepens emotional connections and strengthens relationship dynamics. Trust grows when others feel heard and valued,…
The Ugly Truth About Alcohol’s Effect On Your Brain. Dr Daniel Amen
Reading Time: 6 minutes. Alcohol’s ubiquitous presence in social and cultural settings often belies its insidious impact on the brain, an issue that Dr. Daniel Amen addresses with grave concern. In ‘The Ugly Truth About Alcohol’s Effect On Your Brain,’ Dr Amen, a renowned psychiatrist and brain health advocate, sheds light on the neurological repercussions…
All About Brain Health for Longevity: Insights From Neuroscientist Dr Kristen Willeumier
Reading Time: 6 minutes. In an era where longevity is ever-increasing, understanding the determinants of healthy ageing is paramount. Neuroscientist Dr Kristen Willeumier provides a comprehensive exploration of brain health as a cornerstone of vitality in later years. Her research offers a thorough examination of the physiological and lifestyle factors that influence cognitive longevity, with…
Which Herbal Remedies Have Improved Your Cognition?
Reading Time: 3 minutes. Hey brain health enthusiasts! I’ve been diving deep into the world of herbal remedies and their impact on cognitive function, and I’m eager to share what I’ve learned about two particularly fascinating herbs: Ginkgo biloba and Celastrus paniculatus. Have any of you tried these for boosting your mental clarity and memory?…
Methylene Blue and G6PD Deficiency: Why It Can Be Unsafe
Reading Time: 6 minutes. Methylene blue treats methemoglobinemia via NADPH-dependent reduction to leucomethylene blue. In G6PD deficiency, NADPH is insufficient, so the drug cannot reduce methemoglobin and instead amplifies oxidative stress. This triggers Heinz body formation, acute hemolysis, and can worsen hypoxia. FDA labelling lists G6PD deficiency as a contraindication. Warning signs include dark urine,…
