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Is Long-Term Methylene Blue Use Safe? Contraindications, Daily Dosing Risks, and What Research Really Shows
Reading Time: 21 minutes. Long-term methylene blue use appears safe at therapeutic doses of 0.5-2 mg/kg body weight, with typical protocols using 10-30 mg daily for neurological benefits. Research indicates doses exceeding 5 mg/kg approach toxic territory, causing cardiovascular, gastrointestinal, and haematological complications. The compound exhibits a narrow therapeutic window, where low doses enhance mitochondrial…
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The Fountain of Youth for Our Cells? Let’s Discuss the Latest Anti-Ageing Studies
Reading Time: 3 minutes. Hey everyone! I’ve recently come across some intriguing studies on methylene blue and its potential anti-ageing effects on our cells. Ever heard of it? Let me break down what I’ve found in a way that’s easy to digest and hopefully sparks some interesting discussions. What is Methylene Blue? Methylene blue, a…
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What Science Reveals About Methylene Blue Benefits: From Brain Power and Mitochondrial Energy to Emerging Health Uses
Reading Time: 11 minutes. Science suggests methylene blue can shuttle electrons in the mitochondrial chain, support ATP production, and limit reactive oxygen species via redox cycling. Small trials report modest gains in memory and attention, alongside neuroprotective signals. It is FDA‑approved for methemoglobinemia and used in select surgical contexts. Yet, dosing windows are narrow, MAO…
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Methylene Blue and ALS (Amyotrophic Lateral Sclerosis): Hope or Hype?
Reading Time: 6 minutes. Despite methylene blue‘s compelling biochemical rationale—it enhances mitochondrial function, reduces oxidative stress, and dampens neuroinflammation—you’ll find its track record in ALS research disappointingly underwhelming. The compound showed no survival benefit or motor improvement in SOD1(G93A) mouse models, the gold standard for preclinical ALS testing. While simpler organisms, such as C. elegans,…
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Methylene Blue and Anxiety: What the Research Says About Stress and Resilience
Reading Time: 10 minutes. Methylene blue shows promise as a low-dose, mitochondria-targeted adjunct for anxiety. It preserves neuronal ATP via redox cycling, improves cerebral oxygenation, and reduces oxidative stress. Modest, reversible MAO-A/B inhibition may aid mood and attention, with small studies noting improvements in memory and vigilance. It can enhance fear extinction, supporting exposure-based therapies.…
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Methylene Blue With Nad+: Exploring Synergy in Cellular Energy Support
Reading Time: 6 minutes. Methylene blue (MB) and NAD+ exhibit complementary redox roles that stabilise mitochondrial electron transport. NAD+ accepts hydrides in the Krebs cycle, sustaining Complex I activity, while low-dose MB shuttles electrons and oxidises NADH/NADPH, preserving ATP synthesis under stress. MB transiently activates AMPK and protects telomeres; NAD+ supports sirtuins and PARPs for…
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Methylene Blue for ADHD and Cognitive Enhancement: Separating Fact From Fiction
Reading Time: 4 minutes. Hey, fellow brain enthusiasts! I’ve recently stumbled upon something quite intriguing in the realm of cognitive enhancement—Methylene Blue! This isn’t just any ordinary compound; it has been around in medical circles for a long time but is now gaining attention for its potential benefits in enhancing brain function, particularly for individuals…
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Methylene Blue: A Ray of Hope for Alzheimer’s and Dementia Patients?
Reading Time: 4 minutes. Hey everyone in the Brain Health Blog Forum! I recently came across some intriguing research on Methylene Blue and its potential benefits for patients with Alzheimer’s and dementia. I thought it would be great to share what I’ve learned and see if anyone else here has any insights or experiences with…
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Methylene Blue Dosage Chart by Body Weight: Safe Guidelines With Blu Brain
Reading Time: 6 minutes. You’ll need to calculate the methylene blue dosage based on your body weight to stay within safe therapeutic ranges. Clinical guidelines recommend keeping doses under 2 mg per kilogram, as toxicity begins around 7 mg/kg. For cognitive benefits, research suggests 4-30 mg daily is both safe and effective. The compound follows…
Methylene Blue 1% Mind Booster
Tag: ageing
Understand the process of ageing and its impact on various aspects of health, including brain health and cognitive function.
