-
H3N2 Vs Typical Seasonal Flu: Key Differences Explained
Reading Time: 8 minutes. H3N2 differs from typical seasonal influenza in its greater severity, particularly affecting older adults and individuals with pre-existing conditions. While standard flu strains cause moderate illness, H3N2 produces more aggressive respiratory symptoms, higher hospitalisation rates, and increased mortality risk among vulnerable populations. The strain’s rapid mutation rate reduces vaccine effectiveness in adults…
-
Stress-Proof Your Brain: Techniques for Mental Resilience and Cognitive Health
Reading Time: 3 minutes. I’ve recently come across compelling research on Methylene Blue (MB) and its potential benefits for cognitive health and stress resilience. I thought I’d share what I’ve learned and hear your thoughts or experiences with this intriguing compound. What is Methylene Blue? Methylene Blue is a chemical compound with a rich history…
-
Does Methylene Blue Affect Blood Pressure Levels?
Reading Time: 13 minutes. Methylene blue exhibits significant effects on blood pressure through multiple mechanisms. The drug primarily acts by inhibiting guanylate cyclase, reducing cGMP levels and nitric oxide release, leading to Vasoconstriction and increased vascular tone. Administration typically induces a rapid elevation in mean arterial pressure within 30-60 seconds, with effects normalising in 90…
-
Methylene Blue and Mental Health: From Anxiety and Depression to Neurodegeneration and Recovery Research
Reading Time: 22 minutes. Methylene blue exhibits psychiatric potential through the inhibition of monoamine oxidase A at nanomolar concentrations and the enhancement of mitochondrial complex activity. Randomised controlled trials establish efficacy for residual depressive symptoms in bipolar disorder, with ideal dosing at 15 mg daily producing significant improvements in depression and anxiety measures without manic…
-
Methylene Blue for Traumatic Brain Injury: Research Insights and Safety Factors
Reading Time: 11 minutes. Methylene blue shows promise for traumatic brain injury through multiple neuroprotective mechanisms, including reducing cerebral lesion volumes (2.49 mm³ vs. 3.29 mm³ in controls), decreasing brain oedema, and preserving neuronal integrity. You’ll find that it enhances mitochondrial function, maintains blood-brain barrier integrity, reduces inflammatory cytokines, and improves motor function outcomes in…
-
Methylene Blue and Stroke: Can It Protect the Brain and Aid Recovery?
Reading Time: 9 minutes. Methylene blue shows promise for protecting your brain during stroke by stabilising mitochondrial function and enhancing ATP production, even in oxygen-deprived tissue. In experimental models, it has reduced infarct volumes by 30-50% and extended the therapeutic window when administered within 60 minutes of stroke onset. The compound acts as an alternative electron…
-
Methylene Blue and Huntington’s Disease: What Research Reveals
Reading Time: 9 minutes. Research shows that methylene blue disrupts huntingtin protein aggregates that cause Huntington’s disease by interfering with hydrogen-bonding networks and β-sheet formation. Studies demonstrate it effectively blocks aggregate formation in cell cultures, extends lifespan in Drosophila models, and delays symptom onset in R6/2 mice when treatment begins early. The compound also enhances…
-
Is Long-Term Methylene Blue Use Safe? Contraindications, Daily Dosing Risks, and What Research Really Shows
Reading Time: 21 minutes. Long-term methylene blue use appears safe at therapeutic doses of 0.5-2 mg/kg body weight, with typical protocols using 10-30 mg daily for neurological benefits. Research indicates doses exceeding 5 mg/kg approach toxic territory, causing cardiovascular, gastrointestinal, and haematological complications. The compound exhibits a narrow therapeutic window, where low doses enhance mitochondrial…
Methylene Blue 1% Mind Booster
