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Methylene Blue and the Immune System: Mechanisms, Evidence, and Considerations
Reading Time: 12 minutes. Methylene blue modulates immunity by inhibiting iNOS/NO signalling, suppressing NF-κB and inflammasome activation, and reducing the production of IL-1β, IL-18, IL-6, and MCP-1. It stabilises mitochondrial respiration as an alternative electron carrier, lowers ROS, and boosts ATP, aiding immune cell energetics. It tempers macrophage/neutrophil activation, as well as MMP release. Clinically,…
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Who Should Avoid Methylene Blue? Key Safety Guidelines
Reading Time: 23 minutes. Methylene blue is contraindicated in several patient populations due to significant safety risks. Pregnant women must avoid it entirely (FDA Category X) due to potential fetal harm. Patients with G6PD deficiency face severe hemolysis risks, requiring mandatory screening before treatment. Those taking serotonergic medications (SSRIs, SNRIs, TCAs) must observe a two-week…
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Top 8 Supplements for Memory Loss During Menopause Symptoms
Reading Time: 7 minutes. Memory loss is a common complaint during menopause, due to the decline in estrogen levels. This article covers supplements for memory loss during menopause that can help improve cognitive function and memory. Learn how these nutrients can support your brain health. Key Takeaways Menopause-related cognitive decline can be mitigated with supplements…
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Unlocking the Role of Dopamine in Addiction and Recovery
Reading Time: 6 minutes. As I explore dopamine’s role in addiction and recovery, I find that it’s essential for our brain’s reward system, driving behaviours linked to pleasure and motivation. Dopamine dysregulation is central to addiction, often triggered by substances or behaviours that artificially boost its levels. Recovery involves resetting this balance, helping our brain…
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Methylene Blue Mechanism of Action: How It Works in the Body
Reading Time: 11 minutes. Methylene blue is a redox-active electron shuttle. It accepts electrons from NADPH/NADH to form leucomethylene blue, which reduces Fe3+ methemoglobin to functional Fe2+ haemoglobin. In mitochondria, it bypasses impaired complexes, enhances cytochrome c oxidase efficiency, sustains ATP production, and limits superoxide production. It inhibits NO-stimulated soluble guanylyl cyclase, restoring vascular tone…
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Methylene Blue and Skin Health: Anti-Ageing, Antioxidant, and Photodynamic Insights
Reading Time: 9 minutes. Methylene blue supports skin health via mitochondrial enhancement, antioxidant activity, and photodynamic benefits. It increases fibroblast oxygen consumption and ATP, reduces mitochondrial ROS, and outperforms common antioxidants. Low-dose use promotes collagen and elastin synthesis, thickens 3D skin models, and preserves extracellular matrix by limiting MMPs. It absorbs UVA/UVB rays, mitigates DNA…
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Unlocking the Power of Your Subconscious Mind for Success
Reading Time: 7 minutes. Your subconscious mind greatly influences your success through deeply embedded belief systems and emotional patterns. By accessing theta brain waves (4-7 Hz) through meditation, you’ll tap into ideal states for reprogramming limiting beliefs and installing success-oriented thinking. Daily practices like morning affirmations, visualisation, and shadow work help transform your mental programming…
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Is ADHD a Disability?
Reading Time: 13 minutes. Nearly 4.4% of adults worldwide live with ADHD, yet confusion persists about its classification as a disability. You’ll find that ADHD meets legal disability criteria when it substantially limits major life activities and affects an individual’s abilities to perform everyday activities. This distinction significantly affects workplace accommodations, educational support, and legal…
Methylene Blue 1% Mind Booster
