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Ivermectin Medication Guide: Dosage, Side Effects, and Treatment Uses
Reading Time: 14 minutes. When using ivermectin, you’ll take a dosage based on your body weight, typically 0.15-0.2 mg/kg orally for parasitic infections such as onchocerciasis and strongyloidiasis. It is FDA-approved for these conditions, as well as topically for head lice and rosacea. Watch for side effects such as dizziness, diarrhoea, and allergic reactions, and…
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Methylene Blue and Serotonin/MAOI Risks
Reading Time: 6 minutes. Methylene blue is the first-line, FDA-approved antidote for acquired methemoglobinemia. It accelerates the NADPH-dependent reduction of ferric (Fe3+) to ferrous (Fe2+) haemoglobin via leuco-methylene blue, rapidly restoring the oxygen-carrying capacity. Indicated when methemoglobin levels are≥20–30% or earlier if symptomatic, dosing is 1–2 mg/kg IV (lower in paediatrics), repeatable once. Risks include…
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Methylene Blue and Methemoglobinemia: Medical Uses and Risks
Reading Time: 6 minutes. Methylene blue is the first-line, FDA-approved antidote for acquired methemoglobinemia. It accelerates the NADPH-dependent reduction of ferric (Fe3+) to ferrous (Fe2+) haemoglobin via leucomethylene blue, rapidly restoring oxygen-carrying capacity. Indicated when methemoglobin levels are≥20–30% or earlier if symptomatic, dosing is 1–2 mg/kg IV (lower in paediatrics), repeatable once. Risks include hemolysis…
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Methylene Blue and Ivermectin Treatment for COVID-19
Reading Time: 14 minutes. You’re likely wondering about methylene blue and ivermectin as potential COVID-19 treatments. While methylene blue has shown some promise in laboratory studies and small clinical trials, with improvements in oxygen saturation and respiratory distress, larger randomised controlled trials are needed to establish its efficacy and safety conclusively. On the other hand,…
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Methylene Blue Mechanism of Action: How It Works in the Body
Reading Time: 11 minutes. Methylene blue is a redox-active electron shuttle. It accepts electrons from NADPH/NADH to form leucomethylene blue, which reduces Fe3+ methemoglobin to functional Fe2+ haemoglobin. In mitochondria, it bypasses impaired complexes, enhances cytochrome c oxidase efficiency, sustains ATP production, and limits superoxide production. It inhibits NO-stimulated soluble guanylyl cyclase, restoring vascular tone…
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Alcohol and Methylene Blue: Risks and Interactions
Reading Time: 6 minutes. The combination of alcohol and methylene blue poses significant medical risks due to potential central nervous system interactions. Patients may experience severe neurological disturbances, including mental status changes, coordination difficulties, and expressive aphasia. Additional complications can include elevated blood pressure, pyrexia, tachycardia, and gastrointestinal disturbances. Healthcare providers must conduct thorough patient…
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Methylene Blue Parasites: What Science Says
Reading Time: 6 minutes. Methylene blue shows multi-stage antimalarial activity with nanomolar potency against Plasmodium, including drug‑resistant P. falciparum and P. vivax. It rapidly reduces transmission by targeting gametocytes and oocyst formation, and may enhance the efficacy of ACT. Mechanisms include redox cycling, inhibition of glutathione reductase, and disruption of heme detoxification. Trials report rapid parasite clearance and favourable safety at…
Methylene Blue 1% Mind Booster
