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Methylene Blue and ALS (Amyotrophic Lateral Sclerosis): Hope or Hype?
Reading Time: 6 minutes. Despite methylene blue‘s compelling biochemical rationale—it enhances mitochondrial function, reduces oxidative stress, and dampens neuroinflammation—you’ll find its track record in ALS research disappointingly underwhelming. The compound showed no survival benefit or motor improvement in SOD1(G93A) mouse models, the gold standard for preclinical ALS testing. While simpler organisms, such as C. elegans,…
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Methylene Blue and Kidney Health: Is There a Risk?
Reading Time: 15 minutes. Methylene blue demonstrates both therapeutic potential and significant risks for kidney health. Clinical studies demonstrate nephroprotective properties through the modulation of redox reactions and activation of the Nrf2/ARE pathway, resulting in documented improvements in creatinine clearance and a reduction in tubular injury markers. However, strict medical supervision is essential due to toxicity…
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Methylene Blue for ADHD and Cognitive Enhancement: Separating Fact From Fiction
Reading Time: 4 minutes. Hey, fellow brain enthusiasts! I’ve recently stumbled upon something quite intriguing in the realm of cognitive enhancement—Methylene Blue! This isn’t just any ordinary compound; it has been around in medical circles for a long time but is now gaining attention for its potential benefits in enhancing brain function, particularly for individuals…
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Methylene Blue: A Ray of Hope for Alzheimer’s and Dementia Patients?
Reading Time: 4 minutes. Hey everyone in the Brain Health Blog Forum! I recently came across some intriguing research on Methylene Blue and its potential benefits for patients with Alzheimer’s and dementia. I thought it would be great to share what I’ve learned and see if anyone else here has any insights or experiences with…
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Methylene Blue and Long Covid: Current Theories and Ongoing Research
Reading Time: 11 minutes. Methylene blue is being explored for Long COVID due to antiviral actions (spike–ACE2 blockade, Zn2+ ionophore effects, RdRp inhibition, lysosomal pH elevation) and immunomodulation (NLRP3, NF-κB, PD-1–SHP2). In vitro data show low micromolar inhibition; small acute COVID-19 trials suggest improved SpO2 and inflammatory markers without a clear mortality benefit. Its mitochondrial…
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The Ugly Truth About Alcohol’s Effect On Your Brain. Dr Daniel Amen
Reading Time: 6 minutes. Alcohol’s ubiquitous presence in social and cultural settings often belies its insidious impact on the brain, an issue that Dr. Daniel Amen addresses with grave concern. In ‘The Ugly Truth About Alcohol’s Effect On Your Brain,’ Dr Amen, a renowned psychiatrist and brain health advocate, sheds light on the neurological repercussions…
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Which Herbal Remedies Have Improved Your Cognition?
Reading Time: 3 minutes. Hey brain health enthusiasts! I’ve been diving deep into the world of herbal remedies and their impact on cognitive function, and I’m eager to share what I’ve learned about two particularly fascinating herbs: Ginkgo biloba and Celastrus paniculatus. Have any of you tried these for boosting your mental clarity and memory?…
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Methylene Blue and Depression: Could It Be a Novel Treatment?
Reading Time: 10 minutes. Methylene blue shows genuine promise as a depression treatment, with controlled trials demonstrating effect sizes of 0.71-0.80 at 300mg doses—comparable to FDA-approved antidepressants. You’ll find that it works through multiple mechanisms, including enhancing mitochondrial function, inhibiting monoamine oxidase A, and modulating nitric oxide pathways. It’s even shown effectiveness in bipolar depression…
Methylene Blue 1% Mind Booster
Tag: memory
Discover strategies and techniques to improve memory and enhance cognitive function, including mnemonic devices, memory exercises, and memory-enhancing interventions.
