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Methylene Blue and Huntington’s Disease: What Research Reveals
Reading Time: 9 minutes. Research shows that methylene blue disrupts huntingtin protein aggregates that cause Huntington’s disease by interfering with hydrogen-bonding networks and β-sheet formation. Studies demonstrate it effectively blocks aggregate formation in cell cultures, extends lifespan in Drosophila models, and delays symptom onset in R6/2 mice when treatment begins early. The compound also enhances…
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Is Long-Term Methylene Blue Use Safe? Contraindications, Daily Dosing Risks, and What Research Really Shows
Reading Time: 21 minutes. Long-term methylene blue use appears safe at therapeutic doses of 0.5-2 mg/kg body weight, with typical protocols using 10-30 mg daily for neurological benefits. Research indicates doses exceeding 5 mg/kg approach toxic territory, causing cardiovascular, gastrointestinal, and haematological complications. The compound exhibits a narrow therapeutic window, where low doses enhance mitochondrial…
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World Mental Health Day 2025: How Our Environment Shapes Brain Health
Reading Time: 14 minutes. Our surroundings are not neutral backdrops; they actively shape the way our brains grow and age. The constant assault of urban noise and polluted air inflames the nervous system, disrupts sleep, and drives up rates of anxiety and depression. On the other hand, when we raise children near parks and trees,…
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Revolutionising Health: Mitochondria, Movement, and More
Reading Time: 7 minutes. Your mitochondria act as cellular power plants, producing over 10 million ATP molecules per second through oxidative phosphorylation. Daily movement, particularly walking, triggers mechanical signalling pathways that enhance mitochondrial biogenesis and ATP synthesis efficiency. When you optimise your lifestyle to support mitochondrial function, you’ll boost cellular energy production while protecting against…
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Unravelling Cancer: Lifestyle, Metabolism, and Prevention
Reading Time: 7 minutes. Recent evidence suggests cancer operates primarily as a metabolic disorder, not just a genetic disease. You’ll find that lifestyle factors considerably impact your cellular metabolism and mitochondrial function, with traditional societies exhibiting remarkably lower cancer rates. Through strategic nutritional interventions, regular physical activity, and reduced exposure to environmental toxins, you can…
Methylene Blue 1% Mind Booster
