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Unlocking the Role of Dopamine in Addiction and Recovery
Reading Time: 6 minutes. As I explore dopamine’s role in addiction and recovery, I find that it’s essential for our brain’s reward system, driving behaviours linked to pleasure and motivation. Dopamine dysregulation is central to addiction, often triggered by substances or behaviours that artificially boost its levels. Recovery involves resetting this balance, helping our brain…
Methylene Blue Mechanism of Action: How It Works in the Body
Reading Time: 11 minutes. Methylene blue is a redox-active electron shuttle. It accepts electrons from NADPH/NADH to form leucomethylene blue, which reduces Fe3+ methemoglobin to functional Fe2+ haemoglobin. In mitochondria, it bypasses impaired complexes, enhances cytochrome c oxidase efficiency, sustains ATP production, and limits superoxide production. It inhibits NO-stimulated soluble guanylyl cyclase, restoring vascular tone…
Alcohol and Methylene Blue: Risks and Interactions
Reading Time: 6 minutes. The combination of alcohol and methylene blue poses significant medical risks due to potential central nervous system interactions. Patients may experience severe neurological disturbances, including mental status changes, coordination difficulties, and expressive aphasia. Additional complications can include elevated blood pressure, pyrexia, tachycardia, and gastrointestinal disturbances. Healthcare providers must conduct thorough patient…
Methylene Blue and Skin Health: Anti-Ageing, Antioxidant, and Photodynamic Insights
Reading Time: 9 minutes. Methylene blue supports skin health via mitochondrial enhancement, antioxidant activity, and photodynamic benefits. It increases fibroblast oxygen consumption and ATP, reduces mitochondrial ROS, and outperforms common antioxidants. Low-dose use promotes collagen and elastin synthesis, thickens 3D skin models, and preserves extracellular matrix by limiting MMPs. It absorbs UVA/UVB rays, mitigates DNA…
Methylene Blue Parasites: What Science Says
Reading Time: 6 minutes. Methylene blue shows multi-stage antimalarial activity with nanomolar potency against Plasmodium, including drug‑resistant P. falciparum and P. vivax. It rapidly reduces transmission by targeting gametocytes and oocyst formation, and may enhance the efficacy of ACT. Mechanisms include redox cycling, inhibition of glutathione reductase, and disruption of heme detoxification. Trials report rapid parasite clearance and favourable safety at…
Genetic Testing for ADHD: Personalising Your Treatment Options
Reading Time: 9 minutes. Can genetic testing diagnose ADHD and improve treatment? Yes, genetic testing for ADHD can reveal genetic risk factors and personalise treatment plans. In this article, learn how genetic testing works, its benefits, including reduced side effects, patient experiences, ethical considerations, and future advances. Key Takeaways Understanding Genetic Testing for ADHD Genetic…
Methylene Blue Lyme Disease: Early Research and Findings
Reading Time: 9 minutes. Early laboratory work suggests that methylene blue has activity against the stationary-phase Borrelia burgdorferi and biofilms. Johns Hopkins screening identified it among the top hits, with about 60% persister reductions and enhanced clearance when combined with antibiotics. Mechanisms include ROS-mediated and photodynamic effects, with synergy observed when used in combination with…
Unlocking the Power of Your Subconscious Mind for Success
Reading Time: 7 minutes. Your subconscious mind greatly influences your success through deeply embedded belief systems and emotional patterns. By accessing theta brain waves (4-7 Hz) through meditation, you’ll tap into ideal states for reprogramming limiting beliefs and installing success-oriented thinking. Daily practices like morning affirmations, visualisation, and shadow work help transform your mental programming…
