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Is Long-Term Methylene Blue Use Safe? Contraindications, Daily Dosing Risks, and What Research Really Shows
Reading Time: 21 minutes. Long-term methylene blue use appears safe at therapeutic doses of 0.5-2 mg/kg body weight, with typical protocols using 10-30 mg daily for neurological benefits. Research indicates doses exceeding 5 mg/kg approach toxic territory, causing cardiovascular, gastrointestinal, and haematological complications. The compound exhibits a narrow therapeutic window, where low doses enhance mitochondrial…
Unveiling Natural Supplements for Superior Cognitive Health
Reading Time: 6 minutes. Unveil the secrets to superior cognitive health with natural supplements that unlock the full potential of the mind. Dive into the world of omega-3 fatty acids, B vitamins, gingko biloba, rhodiola rosea, bacopa monnieri, and lion’s mane mushroom. These incredible supplements have been scientifically proven to enhance cognitive function, boost memory,…
Neuroscience Secrets for Enhanced Brain Longevity
Reading Time: 7 minutes. In a world where the mind is constantly bombarded with information, one would think that the brain’s longevity would be enhanced. However, the opposite seems to be true. In this article, we will explore the secrets of neuroscience that can help enhance brain longevity. By understanding the ageing brain, harnessing the…
11 Key Strategies for Enhancing Cognitive Function in Seniors
Reading Time: 9 minutes. Enhancing cognitive function in seniors is a paramount concern for those who desire to serve and support the elderly population. With 11 key strategies at their disposal, caregivers can make a significant impact on the mental well-being of seniors. From nutrition and physical exercise to cognitive stimulation activities and stress management…
Why Proper Brain Health Elevates Students’ Performance
Reading Time: 5 minutes. Proper brain health is the fuel that propels students towards academic success. Like a well-oiled machine, a healthy brain allows students to think critically, retain information, and perform at their best. However, in the hustle and bustle of daily life, it can be easy to neglect this vital aspect of overall…
Enhancing Brain Health: A Holistic Approach to Alzheimer’s
Reading Time: 7 minutes. You can protect your brain health and reduce Alzheimer’s risk through a multi-faceted approach targeting key factors. Focus on optimising nutrition with MCT oil and Omega-3s, maintaining quality sleep, managing stress levels, and reducing exposure to environmental toxins like mould and heavy metals. Your genetic profile, particularly the APOE4 gene, influences…
How to Use Methylene Blue Safely: Dosage by Weight, Risk Factors, and the Blu Brain Calculator
Reading Time: 16 minutes. Methylene blue is a redox-active antidote for methemoglobinemia dosed by weight. Typical dosing is 1 mg/kg IV over 5–30 minutes, diluted in 5% dextrose; avoid sodium chloride. Do not exceed 5 mg/kg/day or 7 mg/kg cumulative (stricter: ≤4 mg/kg for aniline/dapsone). In paediatrics, standard doses are 0.3–1 mg/kg with a single…
Methylene Blue and Anxiety: What the Research Says About Stress and Resilience
Reading Time: 10 minutes. Methylene blue shows promise as a low-dose, mitochondria-targeted adjunct for anxiety. It preserves neuronal ATP via redox cycling, improves cerebral oxygenation, and reduces oxidative stress. Modest, reversible MAO-A/B inhibition may aid mood and attention, with small studies noting improvements in memory and vigilance. It can enhance fear extinction, supporting exposure-based therapies.…
