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Methylene Blue Mechanism of Action: How It Works in the Body
Reading Time: 11 minutes. Methylene blue is a redox-active electron shuttle. It accepts electrons from NADPH/NADH to form leucomethylene blue, which reduces Fe3+ methemoglobin to functional Fe2+ haemoglobin. In mitochondria, it bypasses impaired complexes, enhances cytochrome c oxidase efficiency, sustains ATP production, and limits superoxide production. It inhibits NO-stimulated soluble guanylyl cyclase, restoring vascular tone…
Methylene Blue Parasites: What Science Says
Reading Time: 6 minutes. Methylene blue shows multi-stage antimalarial activity with nanomolar potency against Plasmodium, including drug‑resistant P. falciparum and P. vivax. It rapidly reduces transmission by targeting gametocytes and oocyst formation, and may enhance the efficacy of ACT. Mechanisms include redox cycling, inhibition of glutathione reductase, and disruption of heme detoxification. Trials report rapid parasite clearance and favourable safety at…
Unlocking Health: Insights From Dr John E. Lewis
Reading Time: 5 minutes. I find Dr John E Lewis’s insights on health compelling, especially regarding the’ benefits of polysaccharides for the immune system and brain health. He’s renowned for over 180 nutrition science publications and emphasises whole-food plant-based diets. His shift from competitive bodybuilding to health advocacy focuses on well-being over aesthetics. Dr Lewis…
Unlocking Mental Health Through the Ketogenic Diet
Reading Time: 6 minutes. The ketogenic diet can considerably improve your mental health through its powerful effects on brain function and mood stabilisation. When you switch from glucose to ketones for brain energy, you’ll experience reduced inflammation, balanced neurotransmitters, and enhanced cognitive clarity. Clinical studies show impressive results, with 43% of patients achieving remission from…
Unlocking the Power of Mind-Body Harmony for Wellness
Reading Time: 7 minutes. Your mind and body form an intricate partnership that directly influences your overall wellness. Through the vagus nerve, your thoughts and emotions create physical responses affecting everything from heart rate to immune function. You can enhance this connection through simple daily practices, such as mindful breathing, movement meditation, and emotional awareness…
Unlocking the Gut-Brain Connection for Better Health
Reading Time: 7 minutes. The gut-brain axis operates through a complex network of over 100 million neurons in the enteric nervous system, communicating bidirectionally via the vagus nerve. This connection influences neurotransmitter production, with 90% of serotonin synthesised in the gastrointestinal tract. The gut microbiome’s diversity modulates cognitive function, emotional processing, and stress responses through…
Transforming Healthcare Through Integrative Approaches
Reading Time: 7 minutes. We’re witnessing a revolutionary shift in healthcare as integrative approaches combine conventional medicine with evidence-based natural therapies. Addressing the whole person—including hormonal health, environmental factors, and lifestyle choices—can create more effective treatment strategies. Today’s healthcare professionals embrace personalised protocols that blend traditional medications with natural remedies while focusing on patient education…
Unlocking Creatine: Beyond Muscle to Mind and Gut Health
Reading Time: 6 minutes. I’ll help you understand why creatine isn’t just for bodybuilders. Beyond enhancing muscle performance, creatine plays an essential role in brain function, supporting cognitive health and potentially aiding conditions like ADHD. It impacts gut health by improving nutrient absorption and influences cellular energy production through epigenetic modifications. With 45% of methyl…
Unlocking Wellness Through the Ancient Art of Qigong
Reading Time: 5 minutes. We reveal wellness through qigong by embracing its ancient wisdom, which intertwines movement, breathwork, and meditation to harmonise body, mind, and spirit. The Eight Brocades, a key practice, enhances flexibility, mental clarity, and longevity. Qigong reduces stress, improves immune function, and fosters a deep connection to our inner selves. As we…
